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RNA-Ptoteins
Tubulins
p53 stability
AI Benefit
Onco_separation
Deep learning mutations
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Linear seq:AAAGCERH
Antibody selection
Salt solution
Protein stability
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Improved Drag & Drop with Two Custom Windows and Comparative Analysis Button
tube_alpha1
tube_beta2
tube_alpha3
tube_beta4
GTF
Rigoser
N15
Finish selection1
Finish selection2
Reset selection
Go to comparative analysis?
Improved Drag & Drop with Two Custom Windows and Comparative Analysis Button
tube_alpha1
tube_beta2
tube_alpha3
tube_beta4
GTF
Rigoser
N15
Finish selection1
Finish selection2
Reset selection
Go to comparative analysis?
Interactive Scatter Plot with Custom Hover Window
y-axis Values
I5L: -3.02396753435184E-4
C25PHE: -0.00303229340481579
E55K: 0.0012431342256823
T56M: -3.24814107573892E-4
R64W: -6.30834726177682E-4
L70S: -3.9314914714387E-4
P72S: 1.09178773966691E-4
L92V: 7.77686402514754E-6
N101S: 2.59517407881261E-4
242P: 4.92158403480332E-5
Hover over a dot
Interactive Scatter Plot with Custom Hover Window
y-axis Values
I5L: -3.02396753435184E-4
C25PHE: -0.00303229340481579
E55K: 0.0012431342256823
T56M: -3.24814107573892E-4
R64W: -6.30834726177682E-4
L70S: -3.9314914714387E-4
P72S: 1.09178773966691E-4
L92V: 7.77686402514754E-6
N101S: 2.59517407881261E-4
242P: 4.92158403480332E-5
Hover over a dot
Interactive Scatter Plot with Custom Window
Interactive Scatter Plot with Custom Window
C25PHE
E55K
T56M
R64W
L70S
P72S
L92V
N101S
242P
Hover over a point to see the value
Interactive Scatter Plot with Custom Hover Window
y-axis Values
I5L: -3.02396753435184E-4
C25PHE: -0.00303229340481579
E55K: 0.0012431342256823
T56M: -3.24814107573892E-4
R64W: -6.30834726177682E-4
L70S: -3.9314914714387E-4
P72S: 1.09178773966691E-4
L92V: 7.77686402514754E-6
N101S: 2.59517407881261E-4
242P: 4.92158403480332E-5
Hover over a dot
Interactive Scatter Plot with Tooltips
Interactive Scatter Plot with Tooltips
C25PHE: -0.003032
E55K: 0.001243
T56M: -0.000325
R64W: -0.000631
L70S: -0.000393
P72S: 0.000109
L92V: 0.000008
N101S: 0.000260
242P: 0.000049
C25PHE
E55K
T56M
R64W
L70S
P72S
L92V
N101S
242P
Interactive Scatter Plot – Mutation Data
y-axis Values
I5L: -3.02396753435184E-4
I5L
C25PHE: -0.00303229340481579
C25PHE
E55K: 0.0012431342256823
E55K
T56M: -3.24814107573892E-4
T56M
R64W: -6.30834726177682E-4
R64W
L70S: -3.9314914714387E-4
L70S
P72S: 1.09178773966691E-4
P72S
L92V: 7.77686402514754E-6
L92V
N101S: 2.59517407881261E-4
N101S
242P: 4.92158403480332E-5
242P
Interactive Scatter Plot with Tooltips
Interactive Scatter Plot with Tooltips
C25PHE: -0.003032
E55K: 0.001243
T56M: -0.000325
R64W: -0.000631
L70S: -0.000393
P72S: 0.000109
L92V: 0.000008
N101S: 0.000260
242P: 0.000049
C25PHE
E55K
T56M
R64W
L70S
P72S
L92V
N101S
242P
SVG Scatter Plot – Exact Values (0 at y≈111)
(d)
TUBB mutants were toxic when overexpressed
[tba-tbb-GTP1]
y-axis Values
0
Point 1
-0.00483730426836042
Point 2
-0.00206941308753028
Point 3
-0.00460897458827959
Point 4
-0.00202274133980445
Point 5
5.0241215304543E-5
Point 6
4.93956854759302E-5
Point 7
5.35810073081226E-5
Point 8
-0.00418559768489757
Point 9
-0.00450014848805353
Point 10
-0.00178548245541776
Point 11
-3.02396753435184E-4
Point 12
-0.00303229340481579
Point 13
0.0012431342256823
Point 14
-3.24814107573892E-4
Point 15
-6.30834726177682E-4
Point 16
-3.9314914714387E-4
Point 17
1.09178773966691E-4
Point 18
7.77686402514754E-6
Point 19
2.59517407881261E-4
Point 20
4.92158403480332E-5
Point 21
Upper Graph – Biochemical Mutation Analysis
(d)
TUBB mutants were toxic when overexpressed
[tba-tbb-GTP1]
WT
242P
I5L
C25PHE
E55K
T56M
R64W
L70S
P72S
L92V
N101S
E113K
lg(cond(W))
4.73840
4.73777
4.73715
4.73650
4.73587
4.73523
4.73460
4.73779
4.73784
4.73744
4.73484
4.73830
4.73741
4.73827
4.73743
4.73804
4.73780
4.73774
4.73805
Vector Graph Visualization
4.5190
4.5200
4.5210
4.5220
4.5230
WT (tetramer)
C239F/C239TYR
A248F/A248TYR
lg(cond(WI))
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