Obtain a complete set of physical interaction parameters for Antigen-Fab
2 that have contact through interacting domains.- An example of the PDB structure is given below on the page.
- An example of the obtained calculated data, correlation with experiment and the use of machine learning methods, see below on the page.
You can introduce mutations into one PDB at once, up to 4 mutations at the same time.
It is desirable that the mutations do not occur one after another, but are spaced and separated by other amino acid residues.
The server does not SEARCH FOR THE CONTACT AREA;
it is assumed that the structure's PDB already contains this spatial information.
- To obtain more accurate results, it is necessary to separately analyze mutations in the heavy chain from mutations in the light chain, and separately analyze their simultaneous presence in all chains.