Deep mutational scanning:
a new style of protein science
Calculated on-line server: 3D peptides
Algorithm17

Take advantage of every individual peptide study!
Below is the commercial cost of ordering a small peptide with a given sequence and properties
from commercial producers

When you know more about the object being studied, you work less and you pay less.

Take advantage of modern trends in AI and machine learning to obtain primary data characterizing peptide stability, aggregation, entropy, etc.
Save on each order by having a forecast of experimental data in advance
Obtain a complete set of physical interaction parameters for a dimer of peptides
that have contact through interacting domains.
An example of the PDB structure is given below on the page.
You can introduce mutations into one PDB or into both at once,
up to 4 mutations at the same time.
It is desirable that the mutations do not occur one after another, but are spaced and separated by other amino acid residues.
The server does not SEARCH FOR THE CONTACT AREA;
it is assumed that the structure's PDB already contains this spatial information.
Potential energy interaction map of two polypeptide chains

Online server for calculating thermodynamic properties of similar peptide sequences. You can pay hundreds of euros for the production of each individual peptide, or you can study the properties of 100 different peptides for only 249 Euros

Input data

  • Load PDB file N1 for first peptide structure,
  • select amount of mutaions,
  • Serial number of this a.a. in PDB file,
  • new indicates of a.a.
  • Load PDB file N2 for second peptide structure
  • select amount of mutaions,
  • Serial number of this a.a. in PDB file,
  • new indicates of a.a.
InPut PDB N1 of peptide srtucture
How much mutations in peptide N1 do you need?
The serial number of the substitution (mutation) of the amino acid residue according to the PDB file, if there are several substitutions, then write separated by a space
Indicate the new names of amino acid residues after their replacement for the missense mutation
InPut PDB N2 of peptide srtucture
How much mutations in peptide do you need?

Our service provides a fast and easy way to perform complex bioinformatics calculations. With our user-friendly interface, you can quickly submit your data and get results within minutes. We also offer many advanced features to help you get the most out of your calculations.


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Example of PDB file structure:
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